Promoter methylation represses AT2R gene and increases brain hypoxic–ischemic injury in neonatal rats
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چکیده
منابع مشابه
Methylation Status of SMG1 Gene Promoter in Multiple Myeloma
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BACKGROUND AND PURPOSE Iron catalyzes the formation of damaging reactive species during cerebral reperfusion. Brain iron concentration is highest at birth, so the brain of the asphyxiated newborn may be at increased risk of iron-dependent injury. We investigated whether the ferric iron chelator deferoxamine could reduce hypoxic-ischemic brain injury in neonatal rats. Because deferoxamine has co...
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ژورنال
عنوان ژورنال: Neurobiology of Disease
سال: 2013
ISSN: 0969-9961
DOI: 10.1016/j.nbd.2013.08.011